Ormetoprim

Ormetoprim
Clinical data
Other namesOrmethoprim
Identifiers
IUPAC name
  • 5-[(4,5-Dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.027.497
Chemical and physical data
FormulaC14H18N4O2
Molar mass274.324 g·mol−1
3D model (JSmol)
SMILES
  • CC1=CC(=C(C=C1CC2=CN=C(N=C2N)N)OC)OC
InChI
  • InChI=1S/C14H18N4O2/c1-8-4-11(19-2)12(20-3)6-9(8)5-10-7-17-14(16)18-13(10)15/h4,6-7H,5H2,1-3H3,(H4,15,16,17,18)
  • Key:KEEYRKYKLYARHO-UHFFFAOYSA-N

Ormetoprim is an antibiotic used in veterinary medicine. Typically it is used in combination with sulfadimethoxine, and it is used in the poultry[1] and aquaculture industries.[2]

Ormetoprim, like other diaminopyrimidines such as trimethoprim, inhibits the reduction of dihydrofolic acid to tetrahydrofolic acid by bacterial cells.[3]

References

  1. ↑ Hofacre, Charles L.; Fricke, Jenny A.; Inglis, Tom (2013). "Antimicrobial Drug Use in Poultry". Antimicrobial Therapy in Veterinary Medicine. pp. 569–587. doi:10.1002/9781118675014.ch34. ISBN 978-0-470-96302-9.
  2. ↑ Mukta Singh and Paramveer Singh (2018). "Drugs and chemicals applied in aquaculture industry: A review of commercial availability, recommended dosage and mode of application". Journal of Entomology and Zoology Studies. 6 (6): 903–907.
  3. ↑ "PRIMOR - sulfadimethoxine and ormetoprim tablet". dailymed.nlm.nih.gov.
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