hybridoma

English

Etymology

hybrid + -oma

Noun

hybridoma (plural hybridomas or hybridomata)

  1. (immunology) A hybrid cell engineered from a lymphocyte and a tumour cell; used to generate monoclonal antibodies
    • 1982, Saad A. Noeman, Dhirendra N.Misra, Robert J. Yankes, Heinz W. Kunz, Thomas J. Gill III, “Growth of Rat-mouse hybridomas in nude mice and nude rats”, in Journal of Immunological Methods, →DOI:
      Athymic (nude) mice and rats were inoculated intraperitoneally with rat-mouse hybridoma cells secreting monoclonal antibodies to rat MHC class I antigens in order to improve the yield of antibodies.

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